Exceptional mass accuracy and high-resolution quantification in complex matrices.

Main Features

Advanced quadrupole technology (AQT) for improved quantification of low-abundance analytes in complex matrices
Data-independent acquisition (DIA) and Parallel Reaction Monitoring (PRM) for reproducible quantification with qualitative certainty
Active beam guide (AABG) minimises noise and extends maintenance intervals
Optional mode for intact protein analysis, maximising capture and analysis of large biomolecules and complexes
High-resolution up to 240,000 (at m/z 200) and scan rates up to 12 Hz for compatibility with UHPLC
Mass range: 50 to 6000 m/z
High mass accuracy: <1 ppm in full and AIF scan modes
Dynamic intrascan range over four orders of magnitude; femtogram level sensitivity
Fast polarity switching maximises data output in a single run
Multiple dissociation techniques available, including in-source CID and HCD
Retrospective data analysis via HR/AM and full scan enables complete data capture, eliminating the need for sample re-runs

Specifications

Scan Rate	Up to 12 Hz
Mass Range	50 – 6000 m/z
Maximum Resolution	Up to 240,000 (at m/z 200)
Dynamic Range	>5000:1
Mass Accuracy	<1 ppm (internal & external calibration)
Polarity Switching	Full cycle in <1 s
Type	Quadrupole-Orbitrap LC-MS

Application Benefits

Ideal for both qualitative and quantitative research applications, including DMPK screening and intact monoclonal antibody characterisation
Highly reliable results even in challenging sample matrices
Enables retrospective data analysis without repeated sample runs
Sensitivity suitable for trace and high-abundance compounds in a single scan
Not for use in diagnostic procedures

To contact Thermo Fisher Scientific Australia Pty Ltd about Thermo Scientific Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer use Get a quote.

Main Features

Advanced quadrupole technology (AQT) for improved quantification of low-abundance analytes in complex matrices
Data-independent acquisition (DIA) and Parallel Reaction Monitoring (PRM) for reproducible quantification with qualitative certainty
Active beam guide (AABG) minimises noise and extends maintenance intervals
Optional mode for intact protein analysis, maximising capture and analysis of large biomolecules and complexes
High-resolution up to 240,000 (at m/z 200) and scan rates up to 12 Hz for compatibility with UHPLC
Mass range: 50 to 6000 m/z
High mass accuracy: <1 ppm in full and AIF scan modes
Dynamic intrascan range over four orders of magnitude; femtogram level sensitivity
Fast polarity switching maximises data output in a single run
Multiple dissociation techniques available, including in-source CID and HCD
Retrospective data analysis via HR/AM and full scan enables complete data capture, eliminating the need for sample re-runs

Specifications

Scan Rate	Up to 12 Hz
Mass Range	50 – 6000 m/z
Maximum Resolution	Up to 240,000 (at m/z 200)
Dynamic Range	>5000:1
Mass Accuracy	<1 ppm (internal & external calibration)
Polarity Switching	Full cycle in <1 s
Type	Quadrupole-Orbitrap LC-MS

Application Benefits

Ideal for both qualitative and quantitative research applications, including DMPK screening and intact monoclonal antibody characterisation
Highly reliable results even in challenging sample matrices
Enables retrospective data analysis without repeated sample runs
Sensitivity suitable for trace and high-abundance compounds in a single scan
Not for use in diagnostic procedures

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To contact Thermo Fisher Scientific Australia Pty Ltd about Thermo Scientific Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer use Get a quote.